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Mus musculus (house mouse) mmu-miR-22-3p URS0000096022_10090

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mmu-mir-22: Mmu-mir-22 is a microRNA that is predicted to regulate the gene Arfip2 [PMC3753644]. Co-transfection experiments with synthetic mmu-mir-22 were performed to evaluate its effect on luciferase protein activity [PMC3753644]. Mmu-mir-22 was found to reduce luciferase activity, along with mmu-miR-26a, and their combination had the greatest effect [PMC3753644]. Mmu-mir-22 was also found to regulate targets such as Wasf1, Arpc5, and Nr3c1, which are involved in C2C12 cell differentiation [PMC3753644]. Similar to mmu-miR-133a and mmu-miR-26a, mmu-mir-22 is upregulated during differentiation of C2C12 cells [PMC3753644]. Mmu-mir-22 has predicted binding sites in the 3' UTR of Fbxl19 [PMC3753644]. In a study on antipsychotic drug treatment, mmu-mir-22 was found to be significantly downregulated in the haloperidol treatment group [PMC3622003]. Mmu-mir-22 has also been predicted to target ion channel proteins such as Ank3 and Trpm7 [PMC4668358]. The expression of mmu-mir-22 was found to be upregulated after UVB irradiation in mice [PMC3597329]. Knockout mouse tissues for mmu-mir-22 were obtained for further study [PMC4869178]. The TRE-MiR-22 mouse model was generated by amplifying the coding sequence of mmu-MIR 2 from mouse genomic DNA and cloning it into a plasmid construct [PMC4447420].

mRNA interactions 4 total

Genome locations

Gene Ontology annotations


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This sequence is found in 50 other species

  1. Alligator mississippiensis Ami-Mir-22-P1b_3p (mature (guide))
  2. Anolis carolinensis (green anole) Aca-Mir-22-P1b_3p (mature (guide))
  3. Artibeus jamaicensis (Jamaican fruit-eating bat) aja-miR-22
  4. Ateles geoffroyi (black-handed spider monkey) age-miR-22
  5. Bos taurus Bta-Mir-22-P1b_3p (mature (guide))
  6. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-22
  7. Callorhinchus milii Cmi-Mir-22-P1b_3p (mature (guide))
  8. Canis lupus familiaris (dog) cfa-miR-22
  9. Cavia porcellus cpo-miR-22-3p
  10. Cervus elaphus cel-miR-22-3p
  11. Chrysemys picta bellii (western painted turtle) Cpi-Mir-22-P1b_3p (mature (guide))
  12. Chrysemys picta cpi-miR-22-3p
  13. Columba livia cli-miR-22-3p
  14. Cricetulus griseus (Chinese hamster) cgr-miR-22-3p
  15. Dasypus novemcinctus dno-miR-22-3p
  16. Daubentonia madagascariensis (aye-aye) dma-miR-22
  17. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-22-P1b_3p (mature (guide))
  18. Equus caballus (horse) eca-miR-22
  19. Gallus gallus gga-miR-22-3p
  20. Gekko japonicus Gja-Mir-22-P1b_3p (mature (guide))
  21. Homo sapiens (human) hsa-miR-22-3p
  22. Lagothrix lagotricha (brown woolly monkey) lla-miR-22
  23. Latimeria chalumnae Lch-Mir-22-P1b_3p (mature (guide))
  24. Lemur catta (Ring-tailed lemur) lca-miR-22
  25. Lepisosteus oculatus Loc-Mir-22-P1b_3p (mature (guide))
  26. Macaca mulatta mml-miR-22
  27. Macaca nemestrina (pig-tailed macaque) mne-miR-22
  28. Microcaecilia unicolor Mun-Mir-22-P1b_3p (mature (guide))
  29. Microcebus murinus (gray mouse lemur) mmr-miR-22
  30. Nomascus leucogenys nle-miR-22
  31. Ophiophagus hannah (king cobra) oha-miR-22a
  32. Ornithorhynchus anatinus (platypus) oan-miR-22-3p
  33. Oryctolagus cuniculus (rabbit) ocu-miR-22-3p
  34. Otolemur garnettii (small-eared galago) oga-miR-22
  35. Pan paniscus (pygmy chimpanzee) ppa-miR-22
  36. Pan troglodytes (chimpanzee) ptr-miR-22
  37. Papio hamadryas pha-miR-22
  38. Pongo pygmaeus ppy-miR-22
  39. Pteropus alecto pal-miR-22-3p
  40. Python bivittatus pbv-miR-22-3p
  41. Rattus norvegicus (Norway rat) rno-miR-22-3p
  42. Saguinus labiatus (red-chested mustached tamarin) sla-miR-22
  43. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) sbo-miR-22
  44. Scyliorhinus torazame Sto-Mir-22-P1b_3p (mature (guide))
  45. Sphenodon punctatus (tuatara) Spt-Mir-22-P1b_3p (mature (guide))
  46. Sus scrofa (pig) ssc-miR-22-3p
  47. Taeniopygia guttata (zebra finch) Tgu-Mir-22-P1b_3p (mature (guide))
  48. Tupaia chinensis tch-miR-22-3p
  49. Xenopus laevis Xla-Mir-22-P1b4_3p (mature (co-guide))
  50. Xenopus tropicalis xtr-miR-22-3p