Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
mmu-mir-22: Mmu-mir-22 is a microRNA that is predicted to regulate the gene Arfip2 [PMC3753644]. Co-transfection experiments with synthetic mmu-mir-22 were performed to evaluate its effect on luciferase protein activity [PMC3753644]. Mmu-mir-22 was found to reduce luciferase activity, along with mmu-miR-26a, and their combination had the greatest effect [PMC3753644]. Mmu-mir-22 was also found to regulate targets such as Wasf1, Arpc5, and Nr3c1, which are involved in C2C12 cell differentiation [PMC3753644]. Similar to mmu-miR-133a and mmu-miR-26a, mmu-mir-22 is upregulated during differentiation of C2C12 cells [PMC3753644]. Mmu-mir-22 has predicted binding sites in the 3' UTR of Fbxl19 [PMC3753644]. In a study on antipsychotic drug treatment, mmu-mir-22 was found to be significantly downregulated in the haloperidol treatment group [PMC3622003]. Mmu-mir-22 has also been predicted to target ion channel proteins such as Ank3 and Trpm7 [PMC4668358]. The expression of mmu-mir-22 was found to be upregulated after UVB irradiation in mice [PMC3597329]. Knockout mouse tissues for mmu-mir-22 were obtained for further study [PMC4869178]. The TRE-MiR-22 mouse model was generated by amplifying the coding sequence of mmu-MIR 2 from mouse genomic DNA and cloning it into a plasmid construct [PMC4447420].
mRNA interactions
4 total
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset