eca-mir-205: Eca-mir-205 is a microRNA that has been found to be targeted by multiple DE_circRNAs from host genes EGFR, CATSPERD, ATP2B1, PIWIL2 [PMC9858477]. Another microRNA, Eca-miR-324-5P, is targeted by circRNAs from genes CATSPERB, SPEF2, CAMK2D, and PIWIL2 [PMC9858477]. In a study investigating the expression profile of various microRNAs in mares with endometritis, it was found that eca-miR-100 and eca-mir-205 were differentially expressed and interacted with DECs [PMC9858477]. In the same study, it was observed that eca-miR-155, eca-miR-223, eca-miR-17, eca-miR-200a and eca-mir-205 were overexpressed in both young and old diseased mares compared to control healthy mares [PMC8227551]. Furthermore,e old diseased mares showed higher expression levels of these microRNAs compared to young diseased mares [PMC8227551]. The relative abundance of these microRNAs was also higher in both young and old diseased mares compared to control healthy mares [PMC8227551]. Additionally,e these microRNAs were found to target inflammatory immune response genes such as TRAF6,TNFα , IL6 , IL8 ,and IL10 [PMC8227551]. The study aimed to investigate the expression profile of these microRNAs as well as measure the concentrations of IL6 , PGF2α ,and PGE2 in serum samples from young and old aged mares with healthy and abnormal uterine status (endometritis) [PMC8227551].