gga-mir-205a: gga-mir-205a is a microRNA that has been studied in various contexts. It has been found to be inversely correlated with signal transducer and activator of transcription 3 (STAT3), a key regulator of host immune responses in viral diseases [PMC5983721]. Additionally, gga-mir-205a, along with gga-miR-140-3p and gga-miR-9-5p, is likely involved in downregulating IL-1R1 expression [PMC5983721]. The expression of gga-mir-205a is regulated by the transcription factor myogenin (MyoG), which binds to its gene promoter region [PMC6189278]. The mature sequence of gga-mir-205a consists of 22 nucleotides [PMC6189278]. In the context of heterosis for egg laying in hybrid hens, gga-mir-205a is one of the miRNAs that may be involved in regulating target genes [PMC9563710]. It has also been found that gga-miR-34-5p and gga-mir-205a promote cell apoptosis and are significantly expressed in small yellow follicles of laying chickens and geese, while gga-miR145a5p promotes premature progesterone release in granulosa cells [PMC9563710]. Finally, it was observed that gga-mir-205a was only detected in the top 20 list for one library (BSWF), suggesting a specific role for this miRNA during a specified period [PMC4967221].