v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Canis lupus familiaris (dog) cfa-let-7a URS0000416056_9615

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

cfa-let-7a: Cfa-let-7a is a miRNA that has been found to be involved in aging in dogs [PMC10135127]. It is one of the top five miRNAs that showed significant changes in expression levels [PMC10135127]. Cfa-let-7a, along with three other miRNAs, was used as an endogenous control due to its stable expression [PMC3619122]. In a study on canine chronic lymphocytic leukemia (CLL), the expression pattern of cfa-let-7a was analyzed [PMC3619122]. It was found that cfa-let-7a targets THBS1 and suppresses cellular apoptosis, which may benefit the replication of ORFV in GSF cells [PMC7019303]. THBS1 was downregulated more significantly compared to other cfa-let-7a targets [PMC7019303]. Several miRNA families, including miR-200 and Mirlet-7, were significantly upregulated with testicular RA intervention [PMC4049822]. Cfa-let-7a was found to be significantly upregulated after SAR-related stress compared to rest time [PMC8881509]. The upregulation of cfa-let-7a at T1 compared to T0 was confirmed by qPCR analysis [PMC8881509]. References: [PMC10135127]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135127/ [PMC3619122]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619122/ [PMC7019303]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019303/ [PMC4049822]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049822/ [PMC8881509]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881509/

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
UGAGGUAGUAGGUUGUAUAGUU

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 101 other species

  1. Alligator mississippiensis ami-let-7a-5p
  2. Anolis carolinensis (green anole) aca-let-7a-5p
  3. Ascaris suum (pig roundworm) asu-let-7-5p
  4. Ateles geoffroyi (black-handed spider monkey) microRNA let-7a-1
  5. Blattella germanica Bge-Let-7_5p (mature (guide))
  6. Bos taurus (cattle) bta-let-7a-5p
  7. Branchiostoma belcheri bbe-let-7a-5p
  8. Branchiostoma floridae (Florida lancelet) bfl-let-7a-5p
  9. Branchiostoma lanceolatum (amphioxus) Bla-Let-7-P3_5p (mature (guide))
  10. Brugia malayi (agent of lymphatic filariasis) bma-let-7
  11. Caenorhabditis brenneri cbn-let-7
  12. Caenorhabditis briggsae cbr-let-7
  13. Caenorhabditis elegans cel-let-7-5p
  14. Caenorhabditis remanei crm-let-7
  15. Callithrix jacchus (white-tufted-ear marmoset) cja-let-7a
  16. Callorhinchus milii (elephant shark) Cmi-Let-7-P2b4_5p (mature (guide))
  17. Capra hircus chi-let-7a-5p
  18. Cavia porcellus (domestic guinea pig) cpo-let-7a-5p
  19. Centruroides sculpturatus Csc-Let-7-P18b_5p (mature (guide))
  20. Cervus elaphus (red deer) cel-let-7a
  21. Chiloscyllium plagiosum microRNA cpl-let-7e
  22. Chrysemys picta bellii (western painted turtle) Cpi-Let-7-P2b4_5p (mature (guide))
  23. Chrysemys picta cpi-let-7a-5p
  24. Columba livia cli-let-7a-5p
  25. Crassostrea gigas Cgi-Let-7_5p (mature (guide))
  26. Cricetulus griseus (Chinese hamster) cgr-let-7a
  27. Cyprinus carpio (common carp) ccr-let-7a
  28. Danio rerio dre-let-7a
  29. Dasypus novemcinctus dno-let-7a-5p
  30. Daubentonia madagascariensis (aye-aye) dma-let-7a
  31. Echinops telfairi Ete-Let-7-P2a1_5p (mature (guide))
  32. Eptatretus burgeri Ebu-Let-7-P2o6_5p (mature (guide))
  33. Equus caballus (horse) eca-let-7a
  34. Euprymna scolopes Esc-Let-7_5p (mature (guide))
  35. Gadus morhua gmo-let-7a-5p
  36. Gallus gallus gga-let-7j-5p
  37. Gekko japonicus Gja-Let-7-P2b4_5p (mature (guide))
  38. Gorilla gorilla (western gorilla) microRNA let-7a-1
  39. Haplochromis burtoni abu-let-7a
  40. Heligmosomoides polygyrus hpo-let-7-5p
  41. Homo sapiens (human) hsa-let-7a-5p
  42. Ictalurus punctatus ipu-let-7a
  43. Ixodes ricinus (castor bean tick) iri-let-7-5p
  44. Ixodes scapularis (black-legged tick) Isc-Let-7_5p (mature (guide))
  45. Lagothrix lagotricha (brown woolly monkey) microRNA let-7a-1
  46. Latimeria chalumnae (coelacanth) Lch-Let-7-P2b4_5p (mature (guide))
  47. Lemur catta microRNA let-7a-1
  48. Lepisosteus oculatus Loc-Let-7-P2b4_5p (mature (guide))
  49. Limulus polyphemus (Atlantic horseshoe crab) Lpo-Let-7-P17_5p (mature (guide))
  50. Lingula anatina Lan-Let-7_5p (mature (guide))
  51. Lottia gigantea (owl limpet) lgi-let-7
  52. Macaca mulatta (Rhesus monkey) mml-let-7a-5p
  53. Macaca nemestrina microRNA let-7a-1
  54. Maylandia zebra mze-let-7a
  55. Microcaecilia unicolor Mun-Let-7-P2b4_5p (mature (guide))
  56. Microcebus murinus (gray mouse lemur) mmr-let-7a
  57. Monodelphis domestica mdo-let-7a-5p
  58. Monopterus albus Mal-Let-7-P2b4b_5p (mature (guide))
  59. Mus musculus mmu-let-7a-5p
  60. Nautilus pompilius Npo-Let-7_5p (mature (guide))
  61. Neolamprologus brichardi (lyretail cichlid) nbr-let-7a
  62. Nomascus leucogenys (northern white-cheeked gibbon) nle-let-7a
  63. Octopus bimaculoides Obi-Let-7_5p (mature (guide))
  64. Octopus vulgaris Ovu-Let-7_5p (mature (guide))
  65. Ophiophagus hannah oha-let-7a
  66. Oreochromis niloticus (Nile tilapia) oni-let-7a
  67. Ornithorhynchus anatinus (platypus) Oan-Let-7-P2b4_5p (mature (guide))
  68. Oryctolagus cuniculus ocu-let-7a-5p
  69. Oryzias latipes ola-let-7a
  70. Otolemur garnettii oga-let-7a
  71. Ovis aries oar-let-7a
  72. Pan paniscus ppa-let-7a
  73. Pan troglodytes ptr-let-7a
  74. Papio hamadryas pha-let-7a
  75. Parasteatoda tepidariorum pte-let-7-5p
  76. Penaeus japonicus miR-let7
  77. Petromyzon marinus (sea lamprey) pma-let-7a
  78. Pongo pygmaeus (Bornean orangutan) ppy-let-7a
  79. Pristionchus pacificus ppc-let-7
  80. Pteropus alecto pal-let-7a-5p
  81. Ptychodera flava Pfl-Let-7_5p (mature (guide))
  82. Pundamilia nyererei pny-let-7a
  83. Python bivittatus (Burmese python) pbv-let-7a-5p
  84. Rattus norvegicus (Norway rat) rno-let-7a-5p
  85. synthetic construct RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3'... from None (PDB 4KRF, chain R)
  86. Saccoglossus kowalevskii sko-let-7
  87. Saguinus labiatus microRNA let-7a-1
  88. Saimiri boliviensis boliviensis sbo-let-7a
  89. Salmo salar (Atlantic salmon) ssa-let-7a-5p
  90. Sarcophilus harrisii Sha-Let-7-P2a1_5p (mature (guide))
  91. Scyliorhinus torazame Sto-Let-7-P2b3_5p (mature (guide))
  92. Sphenodon punctatus (tuatara) Spt-Let-7-P2b4_5p (mature (guide))
  93. Sus scrofa ssc-let-7a
  94. Taeniopygia guttata (zebra finch) tgu-let-7a-5p
  95. Takifugu rubripes fru-let-7a
  96. Tetraodon nigroviridis (spotted green pufferfish) tni-let-7a
  97. Tor tambroides (Thai mahseer) let-7a
  98. Tursiops truncatus (common bottlenose dolphin) let-7a
  99. Xenopus laevis (African clawed frog) xla-let-7a-5p
  100. Xenopus tropicalis (tropical clawed frog) xtr-let-7a
  101. Xenoturbella bocki Xbo-Let-7_5p (mature (guide))
 Publications