rno-mir-29c: Rno-mir-29c is a microRNA that is down-regulated in various conditions and has been found to play a role in different biological processes. It has been shown to target DNMT3a and is one of only two microRNAs that target this gene [PMC3596316]. Rno-mir-29c is a member of the miR-29 family, which also includes miR-29a and miR-29b [PMC3895276]. The expression levels of rno-mir-29c have been found to be reduced in the mature rat cochleae [PMC4172914]. Rno-mir-29c has been shown to regulate the expression of various genes, including Period Circadian Regulator 3 (Per3) and Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) [PMC8226960]. Down-regulation of rno-mir-29c has also been associated with enhanced fibrotic response and progression towards heart failure [PMC6377737]. Rno-mir-29c has been found to target members of the DNAJ heat shock protein family (Hsp40) [PMC6377737]. Fish oil supplementation has been shown to alter the expression of rno-mir-29c, as well as other miRNAs, in Sprague Dawley rats with non-alcoholic fatty liver disease (NAFLD) [PMC6321427]. Fish oil feeding can reduce the expression of rno-mir-29c and increase the expression of other miRNAs, such as rno-miR-328 and rno-miR30d, which can regulate genes associated with circadian rhythm, cholesterol metabolism, and liver inflammation [PMC5485288]. Additionally, rno-miR-29a, rno-miR- 29b, and rno-mir-29c have been predicted to regulate the expression of genes involved in bone formation [PMC3273934].