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gga-mir-126: Gga-mir-126 is a microRNA that is abundantly expressed in animal gonads and has been identified in sequencing libraries [PMC3700833]. It is also involved in muscle cell differentiation and energy metabolism [PMC8531282]. In addition, gga-mir-126 has been found to be related to muscle function and expressed in the ovaries of laying chickens [PMC7326969] [PMC9563710]. Studies on mice and zebrafish have shown that miR-126 regulates vascular integrity and angiogenesis by repressing negative regulators of the VEGF pathway [PMC6716571]. Furthermore, gga-mir-126 has been used in inducible expression plasmids to study its effects on gene expression [PMC8235390]. Additionally, gga-mir-126 is one of the precursor miRNAs that showed a reversal in the ratios of the 5p- and 3p-derived sequences across RNA libraries [PMC3511444]. Overall, gga-mir-126 plays a significant role in various biological processes, including gonadal development, muscle function, angiogenesis regulation, and gene expression modulation.
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