ath-miR396b-5p: Ath-mir396b-5p is a microRNA that potentially targets the defense-related gene NONHOST RESISTANCE1 (NHO1) [PMC8080638]. In a study analyzing the interaction networks, ath-mir396b-5p was found to have a higher degree, indicating its central position in the networks [PMC8080638]. Additionally, ath-mir396b-5p was found to have higher degrees in pairs where miRNA was down-regulated while mRNA was up-regulated [PMC8080638]. In another study evaluating the expression of miRNAs in susceptible and resistant biotypes of Echinochloa crus-galli, ath-mir396b-5p showed no over-expression after herbicide treatment and no differences in expression between susceptible and resistant biotypes [PMC9736381]. This suggests that ath-mir396b-5p may not be involved in herbicide resistance mechanisms in E. crus-galli [PMC9736381]. Overall, these findings highlight the potential role of ath-mir396b-5p in regulating defense-related genes and its involvement in interaction networks. However, further research is needed to fully understand its functional significance and potential implications.