eca-mir-200a: Eca-mir-200a is a microRNA that has been found to be overexpressed in old diseased mares compared to young diseased mares and control healthy mares [PMC8227551]. It is part of a group of microRNAs, including eca-miR-155, eca-miR-223, eca-miR-17, and eca-miR-205, that are overexpressed in both young and old diseased mares compared to control healthy mares [PMC8227551]. In particular, eca-mir-200a has been shown to have higher expression levels in old mares compared to young diseased mares and control mares [PMC8227551]. The expression profile of eca-mir-200a and other microRNAs was investigated in the serum of young and old aged mares with healthy and abnormal uterine status (endometritis) [PMC8227551]. These microRNAs have been found to target inflammatory immune response genes such as TRAF6, TNFα, IL6, IL8, and IL10 [PMC8227551]. This study is the first to investigate the expression profile of these microRNAs in mare serum during endometritis [PMC8227551]. The relative abundance of eca-mir-200a was higher in both young and old diseased mares compared to control healthy mares [PMC8227551]. Eca-mir-200a has also been found to regulate the CDC25A gene involved in cell cycle regulation as well as the E2F3 gene [PMC9777602]. These findings suggest that eca-mir-200a could be a potential target for further research on endometritis treatment or diagnosis.