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mmu-mir-143: Mmu-mir-143 is a microRNA that has been studied in various contexts. In one study, miR-143-3p mimic, inhibitor, and miR NCs were transfected into DRG cells, and the expression of mmu-mir-143 was detected using qPCR [PMC6102648]. Another study found that mmu-mir-143 expression levels were increased during adipogenesis and maturation of 3T3-L1 cells [PMC5449966]. Mmu-mir-143 has also been found to be enriched in murine cardiac progenitor cells and during cardiogenesis [PMC7936154]. In mice, the expression of mmu-mir-143 was significantly higher in TM compared to other ocular tissues, and its targeted deletion resulted in increased outflow capacity and reduction of IOP [PMC8237107]. Furthermore, the expression of the mmu-mir-143 cluster is essential for vascular smooth muscle cells to acquire the contractile phenotype [PMC4410957]. Mmu-mir-143 has also been found to be down-regulated by alcohol treatment in a study [PMC6206094]. Additionally, it has been shown that mmu-mir-143 is expressed ubiquitously among organs [PMC1635289]. Furthermore, it was found that Benzo(a)pyrene up-regulates mmu-mir-143 according to miRegulome v1.0 [PMC4525332]. In a network analysis study, mmu-miR-143 was identified as one of the 10 differentially expressed miRNAs with the highest degree [PMC6833270].
mRNA interactions
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