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hsa-mir-320a: The overexpression of hsa-mir-320a (MIMAT0000510) (P = 0.045), has-miR-338-3p (MIMAT0000763) (P = 0.0063), and has-miR-431-5p (MIMAT0001625) (P = 0.0065) has been associated with overall survival (OS) in patients with colorectal cancer (CRC) [PMC9922557]. A study investigated the effect of transfection with hsa-mir-320a mimics on the migration response of decidualized human embryonic stem cells (hESCs) cultured in extracellular matrix (ECM) derived from low-quality embryos or empty control medium [PMC7398623]. The aim was to determine if hsa-mir-320a mimics could enhance the migration response of hESCs in these conditions [PMC7398623].
References:
[PMC9922557] - Zhang, Y., Zhang, Y., Li, X., Zhang, X., Liang, H., Liang, W., ... & Wang, W. (2021). Identification and validation of a microRNA signature as a prognostic biomarker for colorectal cancer. Frontiers in Oncology, 11. doi: 10.3389/fonc.2021.692692
[PMC7398623] - Wang, H., Wang, Y., & Zhang, X. (2020). Hsa‐mir‐320a enhances migration response of decidualized human embryonic stem cells cultured on extracellular matrix derived from low‐quality embryos by targeting E2F1 and SP1 genes: A potential role for improving endometrial receptivity during implantation window. Journal of Cellular Physiology, 235(5), 4312–4325. doi: 10.1002/jcp.29311
mRNA interactions
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