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mmu-mir-320: Mmu-mir-320 is a member of the murine stem-loop mir-320 family and is conserved to hsa-miR-320a-3p [PMC8479292]. Recent evidence suggests that certain miRNAs, including mmu-mir-320, can bypass Drosha processing and enter Dicer machinery directly [PMC5716067]. Mmu-mir-320 has been found to be regulated by the transcription factor Esrrb, along with other miRNAs such as mmu-mir-210, mmu-mir-99b, mmu-mir-499, mmu-mir-196b, mmu-mir-106b, and mmu-mir-32 [PMC9149258]. Additionally, knockout mice for mmu-mir-320 have shown a reduced proportion of oocytes that develop into two-cell and blastocyst stage embryos [PMC9778079]. Mmu-miR-320 has also been identified as a regulator for lung non-specific genes [PMC3866260]. These findings suggest that mmu-miR-320 plays a role in various biological processes and may have implications in diseases such as diabetes mellitus and coronary artery disease. Further research is needed to fully understand the functions and mechanisms of action of this miRNA.
mRNA interactions
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Gene Ontology annotations
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