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mmu-mir-148a: mmu-mir-148a, a microRNA, was knocked out in C57BL/6 J mice using CRISPR/Cas9 technology [PMC9708754]. In a study, fifteen microRNAs, including mmu-mir-148a, were examined [PMC4849059]. Intravenous administration of AAV9 vectors expressing either mmu-mir-148a or an empty control vector was performed [PMC6403487]. The expression of mmu-mir-148a was found to be largely restricted to 10.5 dpc and constituted 16.07% of all miRNAs at that time [PMC1635289]. It was also found to be profuse in sequencing libraries of other animal gonads [PMC4499447]. Furthermore, mmu-miR-375 and mmu-mir-148a were identified as mouse pancreatic β cell-specific miRNAs [PMC7016162]. Among all known mouse miRNAs, 173 known miRNAs were differentially expressed in β cells compared with other cells, including islet-specific miRNA (miR-375) and miR-148a [PMC7016162]. The levels of mmu-miR-375 and mmu-mir-148a in mouse pancreatic β cells were significantly higher than in other cells according to NGS data [PMC7016162].
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