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cfa-mir-30a: Cfa-mir-30a is a member of the cfa-miR-30 family, which is one of the miRNAs with the highest activity in the dog pituitary [PMC4768678]. In a study comparing CFDP1_vs_CFDP2, cfa-mir-30a was found to be significantly downregulated [PMC4768678]. In the adrenal cortex, cfa-mir-30a is part of the cfa-miR-30 family, which is one of the most abundant known miRNAs [PMC4768678]. The expression levels of cfa-mir-30a were validated using qPCR [PMC4768678]. Additionally, in dog adrenal cortex and pituitary samples, cfa-mir-30a was found to be one of the miRNAs with highest activity and abundance [PMC4768678]. In veterinary patients with congestive heart failure (CHF), downregulation of cfa-mir-30a has been observed in canine ventricular and atrial muscles after CHF development subsequent to experimental ventricular pacing [PMC5533140]. The genomic region containing cfa-mir-30a has been identified as a potential location for causal genetic variants related to certain conditions [PMC3485664]. Furthermore, in metastatic and non-metastatic mammary tumors, significant differential expression of cfa-mir-30a has been observed [PMC7646326].
References:
[PMC4768678] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768678/
[PMC5533140] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533140/
[PMC3485664] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485664/
[PM7646326] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646326/
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