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mmu-let-7i: mmu-let-7i is a member of the well-documented let-7 family of microRNAs in T cells, which plays a role in various biological processes, including liver regeneration and the response to obesity [PMC4571067; PMC9198802]. It is associated with mmu-let-7b and mmu-let-7g after hierarchical clustering, but there is no direct evidence of it being grouped with mmu-miR-155 in this context [PMC4099493; PMC3937077]. The gene Acads, involved in fatty acid metabolism, is a putative target of mmu-let-7i [PMC3692539]. In the context of liver regeneration, upregulation of let-7 family members including mmu-let-7i has been observed [PMC9198802]. Additionally, dysregulation of five let-7 family members including mmu-let-7i has been linked to obesity and weight reduction following low-fat diet feeding [PMC4571067]. The expression levels of mmu-let-7i can be quantified using TaqMan® miRNA assays [PMC4077261]. Wild-type and mutated versions of mmu-let-7i are available commercially for research purposes [PMC4238354].
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