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mmu-mir-381: Mmu-mir-381 is a microRNA that has been studied in various contexts. It has been found that the edited form of mmu-mir-381 shares the same seed sequence as mmu-miR-300, although the rest of the sequence differs between the two miRNAs [PMC3409261]. In a study on Ews/Ewsr1 KO mice, it was observed that mmu-mir-381, along with mmu-miR-181a/b/c, was up-regulated in the spinal cord [PMC4989891]. The up-regulation of these miRNAs was associated with the down-regulation of G protein complex in the spinal cord of Ews/Ewsr1 KO mice [PMC4989891]. In another study, it was found that mmu-mir-381 was one of 15 up-regulated miRNAs in a specific order of significance score by SAM [PMC4989891]. Mmu-mir-381 and mmu-miR-181a/b/c were found to suppress Gnai1 and were inhibited by Rgs1 and Rgs19 in the spinal cord of Ews/Ewsr1 KO mice [PMC4989891]. The miRBase accession number for mmu-mir-381 is MI0000798 [PMC3669147]. Additionally, during brown adipocyte differentiation, mmu-mir-381 showed a trend for stronger upregulation along with other miRNAs such as miRPlus_17856 and mmu-miR-501-3p [PMC3070678]. Overall, these studies highlight various aspects and roles of mmu-mir-381 in different biological contexts.
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