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Gallus gallus (chicken) gga-miR-22-3p URS0000096022_9031

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gga-mir-22: Gga-mir-22 is a microRNA that has been found to be significantly increased upon CD40L-stimulation [PMC3743212]. It is also expressed at high levels in HD11 cells [PMC3743212]. Gga-mir-22 has been shown to be differentially expressed in various infection models, including avian influenza virus infection in chicken lungs [PMC5389138], swine-origin H1N1 or avian-origin H7N7 influenza A virus infection in A549 cells [PMC5389138], and highly pathogenic H5N1 avian virus infection in cynomolgus macaques [PMC5389138]. Gga-mir-22 has also been linked to lipid metabolic genes, such as ACSL5, ELVOL6, and PLIN2, suggesting a role in regulating hepatic lipid production during egg production in chickens [PMC7936154]. In addition, gga-mir-22 has been highlighted as being differentially expressed in infected dendritic cells and showed higher expression levels in line 61 compared to line 72 birds after MDV infection [PMC9698451]. The higher expression of gga-mir-22 in line 61 birds may have a protective role against some of the symptoms associated with MDV infection [PMC9698451]. Overall, gga-mir-22 appears to play a role in immune response and lipid metabolism regulation.

Genome locations

Gene Ontology annotations


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This sequence is found in 50 other species

  1. Alligator mississippiensis Ami-Mir-22-P1b_3p (mature (guide))
  2. Anolis carolinensis (green anole) Aca-Mir-22-P1b_3p (mature (guide))
  3. Artibeus jamaicensis (Jamaican fruit-eating bat) aja-miR-22
  4. Ateles geoffroyi (black-handed spider monkey) age-miR-22
  5. Bos taurus Bta-Mir-22-P1b_3p (mature (guide))
  6. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-22
  7. Callorhinchus milii Cmi-Mir-22-P1b_3p (mature (guide))
  8. Canis lupus familiaris (dog) cfa-miR-22
  9. Cavia porcellus cpo-miR-22-3p
  10. Cervus elaphus cel-miR-22-3p
  11. Chrysemys picta bellii (western painted turtle) Cpi-Mir-22-P1b_3p (mature (guide))
  12. Chrysemys picta cpi-miR-22-3p
  13. Columba livia cli-miR-22-3p
  14. Cricetulus griseus (Chinese hamster) cgr-miR-22-3p
  15. Dasypus novemcinctus dno-miR-22-3p
  16. Daubentonia madagascariensis (aye-aye) dma-miR-22
  17. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-22-P1b_3p (mature (guide))
  18. Equus caballus (horse) eca-miR-22
  19. Gekko japonicus Gja-Mir-22-P1b_3p (mature (guide))
  20. Homo sapiens (human) hsa-miR-22-3p
  21. Lagothrix lagotricha (brown woolly monkey) lla-miR-22
  22. Latimeria chalumnae Lch-Mir-22-P1b_3p (mature (guide))
  23. Lemur catta (Ring-tailed lemur) lca-miR-22
  24. Lepisosteus oculatus Loc-Mir-22-P1b_3p (mature (guide))
  25. Macaca mulatta mml-miR-22
  26. Macaca nemestrina (pig-tailed macaque) mne-miR-22
  27. Microcaecilia unicolor Mun-Mir-22-P1b_3p (mature (guide))
  28. Microcebus murinus (gray mouse lemur) mmr-miR-22
  29. Mus musculus mmu-miR-22-3p
  30. Nomascus leucogenys nle-miR-22
  31. Ophiophagus hannah (king cobra) oha-miR-22a
  32. Ornithorhynchus anatinus (platypus) oan-miR-22-3p
  33. Oryctolagus cuniculus (rabbit) ocu-miR-22-3p
  34. Otolemur garnettii (small-eared galago) oga-miR-22
  35. Pan paniscus (pygmy chimpanzee) ppa-miR-22
  36. Pan troglodytes (chimpanzee) ptr-miR-22
  37. Papio hamadryas pha-miR-22
  38. Pongo pygmaeus ppy-miR-22
  39. Pteropus alecto pal-miR-22-3p
  40. Python bivittatus pbv-miR-22-3p
  41. Rattus norvegicus (Norway rat) rno-miR-22-3p
  42. Saguinus labiatus (red-chested mustached tamarin) sla-miR-22
  43. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) sbo-miR-22
  44. Scyliorhinus torazame Sto-Mir-22-P1b_3p (mature (guide))
  45. Sphenodon punctatus (tuatara) Spt-Mir-22-P1b_3p (mature (guide))
  46. Sus scrofa (pig) ssc-miR-22-3p
  47. Taeniopygia guttata (zebra finch) Tgu-Mir-22-P1b_3p (mature (guide))
  48. Tupaia chinensis tch-miR-22-3p
  49. Xenopus laevis Xla-Mir-22-P1b4_3p (mature (co-guide))
  50. Xenopus tropicalis xtr-miR-22-3p