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ssc-mir-183: Ssc-mir-183 is a microRNA that has been detected in early-stage colorectal neoplasia in APC1311 pigs [PMC5707088]. It is one of the ten differentially expressed miRNAs that have been validated by qRT-PCR in this study [PMC5707088]. In more advanced HG-IEN samples, the levels of ssc-mir-183 were significantly elevated compared to LG-IEN samples [PMC5707088]. Similarly, elevated levels of mir-183 have been associated with human colorectal carcinogenesis [PMC5707088]. Ssc-mir-183 has also been found to be upregulated at 1W compared with BW in a study involving pigs [PMC8367414]. Additionally, ssc-mir-183 has higher expression levels in mpiPSCs compared to hpiPSCs [PMC4934789]. In the lungs of Landraces' pigs, ssc-mir-183 was consistently upregulated at 3 dpi, 5 dpi, and 7 dpi [PMC5381705]. In Tongcheng pigs' lungs, ssc-mir-183 was one of the most upregulated microRNAs at different time points after infection with a specific pathogen [PMC5381705]. Ssc-mir-183 is one of the four differentially expressed miRNAs detected in this study that have been reported previously [PMC7222822]. It is also one of the six common miRNAs found among three pairs in another study involving pigs and E. coli infection susceptibility [PMC7222822]. Ssc-mir-183 is regulated by three different transcription factors along with five other miRNAs that are upregulated in E. coli F18-susceptible pigs [PMC3427155].
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