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cfa-mir-98: Cfa-mir-98 is an upregulated microRNA (miRNA) that has been found to be associated with various conditions in dogs. It has been shown to be upregulated in dogs with mild to moderate cardiac enlargement or congestive heart failure, as well as in dogs with different stages of heart disease [PMC5533140] [PMC4964495] [PMC7480022] [PMC9607079]. Additionally, cfa-mir-98 has been found to have a statistically significant correlation with worm burden in the small intestine of dogs [PMC7480022]. It is one of the miRNAs that are present in the tissue of a normal dog [PMC7480022]. In terms of expression, cfa-mir-98 has shown an increasing trend towards the distal segments of the small intestine, while being downregulated in stage C/D dogs compared to stage A dogs [PMC7480022] [PMC9607079]. Furthermore, cfa-mir-98 is one of the miRNAs that significantly differ between different stages of heart disease (B1/B2 and C/D) and stage A dogs [PMC4490541]. Overall, cfa-mir-98 plays a role in cardiac enlargement and heart disease progression.
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