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ssc-miR-103: Ssc-mir-103 is a member of the miR-103/107 family, which has been shown to attenuate miRNA biosynthesis by targeting Dicer [PMC3770649]. It has been observed that the down-regulation of ssc-mir-103 during myofiber formation and maturation may affect myogenesis [PMC3770649]. Ssc-mir-103, along with ssc-miR-15b, ssc-miR-16, and ssc-miR-221-3p, has been found to have different expressions in the myofiber between lean and obese pig breeds [PMC7552122]. Ssc-mir-103 and ssc-miR-221-3p have also been associated with meat quality [PMC7552122]. Ssc-mir-103 is potentially involved in regulating leukocyte migration and chemokine activity by targeting genes such as CDC42, CXCL12, VEGFD, CCL25, CXCL14, and CXCL16 [PMC8851844]. Ssc-mir-103 is one of the ten miRNAs that have been selected as reference genes in different porcine tissues and breeds [PMC3438195]. It has also been found to be abundantly expressed in LPS-treated PBMCs [PMC7903524]. In tooth development studies, ssc-mir-103 has shown expression in various tissues such as enamel epithelium, dental mesenchyme, stellate reticulum, and different types of teeth at different stages [PMC4696248]. In castrated male pigs, down-regulation of ssc-mir-103 has been observed along with other miRNAs involved in the TGF-beta signaling pathway for fat deposition [PMC3901342]. Among conserved miRNAs expressed abundantly are ssc-mir-103, ssc-let-7a, ssc-miR-140-3p, ssc-miR-199a-3p, and ssc-miR-199b-3p [PMC5815207].
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