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bta-miR-320a: Bta-mir-320a is a microRNA that has been found to be highly abundant and differentially expressed in various studies involving cattle [PMC5341059] [PMC4517789] [PMC4990326]. It has been shown to exhibit a significantly differential expression pattern between different cattle breeds [PMC5341059]. Bta-mir-320a is one of the miRNAs that follow a pattern of variant expression, where there is no predominant isomiR [PMC4517789]. It has also been found to have different expression levels during different seasons [PMC4990326]. Bta-mir-320a, along with other miRNAs, has been identified as a regulator in glucose and lipid metabolism in cattle [PMC4090223]. It targets genes such as adenosine monophosphate-activated protein kinase alpha 1 (PRKAA1), peroxisome proliferator-activated receptor-gamma (PPARG), and peroxisome proliferator-activated receptor-alpha (PPARA) [PMC4090223]. Bta-mir-320a is located on bovine chromosomes 8 and 20, with two isoforms identified [PMC4090223]. It has also been found to be highly abundant in certain conditions such as subclinical mastitis and dairy cows' dry secretions [PMC10000098] [PMC9445238]. Overall, bta-mir-320a plays a significant role in various biological processes and may have potential implications for cattle breeding and health.
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