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mmu-mir-152: mmu-mir-152 is a microRNA that has been identified as a regulator for lung non-specific genes [PMC3866260]. It is part of a 9-microRNA group that is down-regulated during the early phase of wound healing and returns to basal levels during the later phase [PMC3665798]. mmu-mir-152 has been found to combine with CaMK II alpha to inhibit the innate immune response induced by DCs, leading to the down-regulation of IL-12, IL-6, TNF-alpha, and IFN-beta synthesis [PMC4136864]. It has also been shown to play a critical role in inducing immune tolerance in liver grafts in a murine model [PMC4136864]. mmu-mir-152 can modify RNA degradation, endocytosis, sphingolipid metabolism, and phosphatidylinositol signaling system [PMC4136864]. Additionally, mmu-mir-152 inhibits DKK1 and is abundantly expressed in hair follicles [PMC8616136]. These findings suggest that mmu-mir-152 may have potential clinical applications as a regulator of immune response and tolerance induction.
mRNA interactions
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