ssc-mir-152: Ssc-mir-152 is a microRNA that has been found to be down-regulated in response to LPS stimulation in porcine PBMCs [PMC7903524]. It is one of the four known miRNAs (along with ssc-miR-122, ssc-miR-129b, and ssc-miR-17-5p) that showed expression changes in response to LPS stimulation [PMC7903524]. Overexpression of miR-17-5p has been shown to inhibit the expression of IL-1β and TNF-α in macrophages [PMC7903524]. Ssc-mir-152 is modestly expressed in porcine PBMCs [PMC7903524]. It has also been found to be down-regulated in pigs susceptible to E. coli F18 infection [PMC3427155]. Ssc-mir-152 has been identified as a potential disease marker for E. coli F18 infection and as a potential regulator of genes such as CREBL1 and HSPA1A [PMC4585011] [PMC3490867]. It is also differentially expressed in different pig breeds, such as the Piétrain breed [PMC3555835]. Ssc-mir-152 is one of the dominant expressed miRNAs in porcine tissues such as duodenum and PPV-infected cells [PMC4545981] [PMC3901342]. It has also been predicted to target FTO, a gene associated with obesity, in castrated male pigs [PMC3901342].