cfa-mir-206: Cfa-mir-206 is a highly expressed miRNA in skeletal muscle [PMC4989286]. It is one of the 5 TE miRNAs found in both the dog heart and skeletal muscle [PMC4989286]. Transient elevations of cfa-mir-206 in the serum were observed, but they were not correlated with any microscopic findings and may be due to injury during animal handling [PMC4989286]. Cfa-mir-206 was included in a panel of miRNAs evaluated for heart, muscle, brain, sciatic nerve, testis, pancreas, and liver tissues [PMC4989286]. It was also selected as one of the 22 miRNAs for qPCR validation as a biomarker candidate for muscle toxicity [PMC4989286]. Downregulation of cfa-mir-206 was observed at 36 dpi and was associated with an attenuated inflammatory response by targeting tcf7l2 [PMC9558963]. Tcf7l2 is a potential target gene of cfa-mir-206 and is involved in various cellular processes such as cell-cell signaling and regulation of response to stimulus [PMC9558963]. Cfa-mir-206 has also been implicated in canine atrial fibrillation, with increased expression observed during atrial fibrillation induced by right atrial tachypacing [PMC4490541] [PMC5533140].
Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset
View annotations in different species by clicking on species names.
Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.