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Rattus norvegicus (Norway rat) rno-miR-206-3p URS000034B6F5_10116

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rno-mir-206: rno-mir-206 is a muscle-specific miRNA that plays a crucial role in muscle cell proliferation, differentiation, apoptosis, migration, and angiogenesis [PMC5270432]. Increased expression levels of rno-mir-206 in cerebral ischemia have been associated with the progression of injury [PMC5270432]. However, marginal downregulation of rno-mir-206 and rno-miR-494-3p at 6 hours post ischemia may contribute to the promotion of recovery [PMC5270432]. In a rat model of cerebral ischemia, underexpression of rno-mir-206 at 72 hours post MCAO was observed, leading to neurogenesis and explaining the spontaneous recovery observed in the rat model [PMC5270432]. Overexpression of rno-mir-206 was found to inhibit neural cell viability [PMC5270432]. Other miRNAs such as miR-214, miR-223, miR-298, miR-327, and miR-494 have also been reported to be overexpressed during ischemia/reperfusion periods in rat models [PMC7555634]. Expression levels of rno-mir-206 correlated well with infarct volumes in a rat model with high R values [PMC3688919]. Expression levels of rno-mir-206 increased from 0 hrs to 24 hrs and gradually decreased from 48 hrs to 168 hrs post-ischemia/reperfusion [PMC3688919]. Rno-mir-206 is known to be abundant in muscle tissue but has also been reported in the rat hippocampus and striatum [PMC9833481]. Additionally, rno-miR-183/96, rno-miR30b,rn0o-rmi-R150,andrnomi-Rn6o-were foundtodysregulatedin two or more studies, suggesting that various factors could influence miRNA expression [PMC10045079].

mRNA interactions 1 total

Genome locations

Gene Ontology annotations


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This sequence is found in 52 other species

  1. Alligator mississippiensis (American alligator) ami-miR-206-3p
  2. Anolis carolinensis (green anole) Aca-Mir-1-P2_3p (mature (guide))
  3. Bos taurus (cattle) bta-miR-206
  4. Callithrix jacchus cja-miR-206
  5. Canis lupus familiaris (dog) cfa-miR-206
  6. Cavia porcellus (domestic guinea pig) cpo-miR-206-3p
  7. Chrysemys picta bellii (western painted turtle) Cpi-Mir-1-P2_3p (mature (guide))
  8. Chrysemys picta (Painted turtle) cpi-miR-206-3p
  9. Columba livia cli-miR-206-3p
  10. Cricetulus griseus cgr-miR-206
  11. Cyprinus carpio (common carp) ccr-miR-206
  12. Danio rerio dre-miR-206-3p
  13. Dasypus novemcinctus dno-miR-206-3p
  14. Echinops telfairi Ete-Mir-1-P2_3p (mature (guide))
  15. Equus caballus (horse) eca-miR-206
  16. Gadus morhua gmo-miR-206-3p
  17. Gallus gallus (chicken) gga-miR-206
  18. Gekko japonicus Gja-Mir-1-P2f_3p (mature (guide))
  19. Gorilla gorilla gorilla ggo-miR-206 (MIR206)
  20. Gorilla gorilla (western gorilla) ggo-miR-206
  21. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-206
  22. Homo sapiens hsa-miR-206
  23. Ictalurus punctatus ipu-miR-206
  24. Latimeria chalumnae Lch-Mir-1-P2_3p (mature (guide))
  25. Lepisosteus oculatus Loc-Mir-1-P2_3p (mature (guide))
  26. Macaca mulatta mml-miR-206
  27. Macaca nemestrina mne-miR-206
  28. Maylandia zebra (zebra mbuna) mze-miR-206
  29. Microcaecilia unicolor Mun-Mir-1-P2_3p (mature (guide))
  30. Monodelphis domestica Mdo-Mir-1-P2_3p (mature (guide))
  31. Monopterus albus Mal-Mir-1-P2a_3p (mature (guide))
  32. Mus musculus mmu-miR-206-3p
  33. Neolamprologus brichardi nbr-miR-206
  34. Ophiophagus hannah (king cobra) oha-miR-206
  35. Oreochromis niloticus oni-miR-206
  36. Ornithorhynchus anatinus (platypus) oan-miR-206-3p
  37. Oryctolagus cuniculus ocu-miR-206-3p
  38. Ovis aries Pri-miR206
  39. Pan troglodytes ptr-miR-206
  40. Paralichthys olivaceus pol-miR-206-3p
  41. Pongo pygmaeus (Bornean orangutan) ppy-miR-206
  42. Pteropus alecto (black flying fox) pal-miR-206-3p
  43. Pundamilia nyererei pny-miR-206
  44. Python bivittatus (Burmese python) pbv-miR-206-3p
  45. Salmo salar ssa-miR-206-3p
  46. Sarcophilus harrisii Sha-Mir-1-P2_3p (mature (guide))
  47. Sphenodon punctatus Spt-Mir-1-P2_3p (mature (guide))
  48. Taeniopygia guttata Tgu-Mir-1-P2_3p (mature (guide))
  49. Tetraodon nigroviridis Tni-Mir-1-P2a_3p (mature (guide))
  50. Tor tambroides (Thai mahseer) miR-206-3p
  51. Xenopus laevis (African clawed frog) xla-miR-206-3p
  52. Xenopus tropicalis xtr-miR-206