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dre-mir-122: Dre-mir-122 is a specific type of microRNA that is associated with the liver in zebrafish [PMC5308255]. In a study, it was found that the expression of dre-mir-122 was down-regulated in the liver of zebrafish injected with MCs [PMC5308255]. Other miRNAs, such as dre-miR-21 and dre-miR-27b, were found to be elevated in expression levels in the liver [PMC5308255]. Dre-mir-122 was also found to be upregulated after exposure to BPA in adult male zebrafish liver [PMC5664119]. In another study, it was observed that dre-mir-122 upregulation was associated with dysregulated metabolism and apoptosis in the liver of gankyrin transgenic zebrafish [PMC5664119].
Dre-mir-122 is specific to the liver, while other miRNAs such as dre-miR-135c and dre-miR-734 are highly expressed in the brain, and dre-miR-499 is enriched in the heart [PMC4647824]. In a comparison between male and female groups, it was found that dre-mir-122 expression was higher in ovaries compared to testes [PMC9495813].
Furthermore, RNA sequencing analysis revealed that TnP treatment altered gene expression levels including upregulation of miRNAs such as miR-21 and miR-26 (dre-miR) [PMC8268205]. Dre-mir-122 also showed differential expression during A. salmonicida infection in S. maximus spleen [PMC8301059].
In summary, dre-mir-122 is a specific microRNA associated with the liver. Its expression can be influenced by various factors such as exposure to BPA or infection. It plays a role in liver metabolism and apoptosis and shows differential expression in different tissues and conditions.
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