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gga-mir-451: Gga-mir-451 is a microRNA that has been found to target the YWHAZ gene [PMC5979595]. It has been shown to inhibit the proliferation and cell cycle progression of DF-1 cells infected with MG, a strain of Mycoplasma gallisepticum, and induce cell apoptosis [PMC5979595]. To further investigate the potential functions of gga-mir-451 in MG-HS infection, DF-1 cells were transfected with miR-451-M or miR-451-NC and then co-cultured with MG-HS for different time periods [PMC5979595]. The study examined the effects of gga-mir-451 on cell behavior in response to MG-HS infection over 24 hours, 48 hours, and 72 hours [PMC5979595]. The results of this study provide insights into the role of gga-mir-451 in regulating cell behavior during MG-HS infection and suggest that it may play a role in modulating cellular responses to this pathogen [PMC5979595]. Further research is needed to fully understand the mechanisms by which gga-mir-451 influences cellular responses during MG-HS infection and its potential as a therapeutic target for controlling Mycoplasma gallisepticum infections in poultry.
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