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sly-miR156d-5p: sly-mir156d-5p is an up-regulated microRNA (miRNA) that was identified and shown to be expressed differently in stem and callus tissue [PMC7745965]. It is predicted to target the promoter binding protein (SBP) domain SQUAMOSA [PMC7745965]. Additionally, sly-mir156d-5p targets the same genes as sly-miR156e-5p and sly-miR156a, including solyc05g015840.2, solyc12g038520.1, solyc10g078700.1, solyc05g015510.2, solyc05g012040.2, and solyc04g045560.2 [PMC7745965]. Another target of sly-mir156d-5p is the lncRNA Lnc_000257 [PMC9295719]. In S. pennellii, sly-mir156d-5p targets Lnc_000990 [PMC9295719].
On the other hand, sly-miR156e-5p is a down-regulated miRNA that was also identified in stem and callus tissue [PMC7745965]. It is predicted to target the SBP domain SQUAMOSA as well [PMC7745965]. Additionally, it targets the same genes as sly-mir156d-5p and sly-miR156a in tomato [PMC7745965]. In terms of lncRNAs targeted by sly-miR156e-5p in tomato (Solanum lycopersicum), Lnc_000257 and Lnc_000976 are targeted by this miRNA [PMC9295719].
In S. pennellii (wild tomato), both sly-mir156d-5p and sly-miR395a target two lncRNAs: Lnc_000990 for mirS.lyr-MIR156d and Lnc_000976 for mirS.lyr-MIR156e [PMC9295719]. Additionally, sly-miR5302a and sly-miR6022 also target these two lncRNAs [PMC9295719].
Overall, sly-mir156d-5p and sly-miR156e-5p are differentially expressed miRNAs in tomato, with distinct target genes and lncRNAs in both tomato and S. pennellii [PMC7745965][PMC9295719].
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