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chi-mir-1: Chi-mir-1 is a downregulated DEmiRNA that targets TMEM173, a major stimulator in IFN production, in PPRV-infected cells [PMC6048839]. It is also downregulated in mock-infected goat PBMC compared to PPRV-infected cells [PMC6048839]. Chi-mir-1 is highly expressed throughout the four sampled stages of the longissimus dorsi muscle of goats [PMC5087842]. It is one of the top 10 DEmiRNAs expressed in these stages [PMC8314457]. Chi-mir-1 is highly abundant and detected in 10.59% of all known miRNAs [PMC5087842]. It targets tumor necrosis factor receptor superfamily member TNFRSF9 genes [PMC6048839]. In addition, chi-mir-1 binds to lncRNA MSTRG.1705.1 and circRNA9106, acting as a sponge for multiple miRNAs [PMC9478897] [PMC8226234]. Chi-mir-1 and chi-mir-133a-3p are overexpressed in the goat endometrium on day 16 of pregnancy compared to nonpregnancy, potentially targeting different genes for various physiological roles with overlapping functions between them [PMC8004627]. Overall, chi-mir-1 plays a significant role in various biological processes and regulatory networks.
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