bta-miR-1: Bta-mir-1 is a specific-related skeletal muscle development miRNA [PMC7802253]. Bta-mir-1 is also more highly expressed than bta-miR-365-3p in early myoblast differentiation, suggesting its importance in the early differentiation stage [PMC7802253]. Bta-miR-365-3p, on the other hand, has higher expression in adult muscle tissues compared to fetal stages, similar to bta-mir-1 [PMC7802253]. Bta-mir-1 is downregulated in extracellular vesicles (EVs) released by competent embryos and upregulated in EVs secreted by arrested embryos [PMC7727673]. It has been proposed that upregulated miRNAs like bta-mir-1 in EVs from good-quality embryos may block cell functions required for normal embryo development [PMC7727673]. Bta-mir-1 has also been detected in the culture medium of bovine embryos and is related to embryo competence [PMC7727673]. Oil treatment has negligible effects on miRNA expression, except for a differential expression of bta-mir-1 between control and CLA groups on day -21 AP [PMC9445238]. Bta-mir-143 is the most significantly upregulated miRNA, while bta-mir-187 is the most significantly downregulated miRNA [PMC9445238]. Bta-miR-206 and bta-miR133a are muscle-specific miRNAs that are highly expressed in bovine skeletal muscles and have been detected frequently across different studies [PMC5003961] [PMC5996145]. The binding site of circ0014518 and bta-mir-1 has been verified using a double luciferase reporter gene system [PMC7726199]. Bta-mir-1, along with bta-mir-133a, bta-mir-206, and bta-mir-378, may contribute to the regulation of muscle growth and phenotype [PMC4090223].