hsa-mir-10a: Hsa-mir-10a is a microRNA that has been extensively studied in various contexts [PMC6740005]. In a study assessing the importance of different variables in model predictions, hsa-mir-10a was found to have a mean importance of 13.02 [PMC9221847]. It is part of a 3-miRNA signature (hsa-miR-20a, hsa-miR-21, hsa-mir-10a) that can stratify GBM patients and contribute to overall survival prediction [PMC9221847]. Hsa-mir-10a has also been identified as a potential biomarker for gastric cancer, showing high accuracy in discriminating different tissue types [PMC6485221]. In Drosophila, hsa-mir-10a shows overall similarity with certain human miRNAs [PMC2486268]. Hsa-mir-10a has been used as a putative non-functional control in experiments involving T-cells and primary CD4 T cells [PMC4118195]. It is one of the down-regulated miRNAs in certain cancer types, accounting for 22.9% of differentially expressed miRNAs [PMC4671457]. Hsa-mir-10a has also been studied for its target genes and its role in various pathways, such as G-Protein Signalling Modulator 1 (GPSM1) and PKDCC pathways [PMC5777794]. It is part of several gene target networks along with other miRNAs such as hsa-let-7g and hsa-miR-26b [PMC8244200]. Hsa-mir-10a has also been implicated in the prognosis and progression of certain diseases such as tuberculosis and chronic myeloid leukemia [PMC5521900] [PMC5368269]. It has been shown to have functional roles in disease progression and the regulation of gene expression [PMC7850735].
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