bta-mir-125a: Bta-mir-125a is a miRNA that has been identified as having significant regulatory immune functions. It has been found to be correlated with the expression of genes WDPCP, VMAC, and ITGA10 [PMC7242321]. Bta-mir-125a is one of the most abundant miRNAs found in commercial milk and is known to have immunological roles that are not affected by pasteurization, homogenization, or heat treatment [PMC10094152]. It has also been identified as a hub miRNA in the regulation of genes such as PIK3CB, VEGFA, MAPK14, PIK3R1, and CASP3 [PMC5831392]. The levels of bta-mir-125a have been found to vary during pre-implantation embryo development [PMC5662615]. Bta-mir-125a is one of the 13 immune-related miRNAs that are among the top 20 most abundant miRNAs in bovine samples [PMC7070426]. It has also been found to be a member of the eumetazoan mir-10 family and has three orthologs in cattle [PMC5390025]. Bta-mir-125a has similarities with human miRNA hsa-miR-99b/let-7e/miR-125a cluster and plays a role in stabilizing the suppressive phenotype of antigen presenting cells [PMC6950176]. Additionally, bta-mir-125a has been found to be differentially expressed during early pregnancy in cattle [PMC6418173]. It is regulated in both MC and SM fractions [PMC5325256] and also has orthologs in F. hepatica [PMC8036276]. Overall, bta-mir-125a is an abundant immune-related miRNA with significant regulatory functions in various biological processes.