ssc-mir-19a: Ssc-mir-19a is a pig-encoded DE miRNA that has been shown to target pre-miRNA ssc-mir-21 [PMC7329775]. It is differentially expressed and plays a role in the urea cycle [PMC5043173]. Ssc-mir-19a has been found to target TNFα, IL-12α, IL-20, and other genes involved in immune response [PMC4778948]. It is one of the five overlapping DEmiRNAs used for gene ontology and pathway analyses in the DAVID software to understand miRNA regulatory function in different pig breeds [PMC4536519]. Ssc-mir-19a has also been found to target HSPA1A and is expressed in castrated male pigs [PMC3490867] [PMC3901342]. It has been shown to regulate PRRSV infection by targeting key receptors or directly targeting the virus genome [PMC10000162]. Its expression has been found to increase in response to treatment in a qRT-PCR study [PMC10000162]. Additionally, ssc-mir-19a has been predicted to target NRF2 and GCLC genes involved in oxidative stress response and glutathione synthesis, respectively [PMC7426424].
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