Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Gallus gallus (chicken) gga-miR-19a-3p URS000006FDD4_9031

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

gga-mir-19a: Gga-mir-19a is a microRNA that has been found to positively regulate the activity of the NF-κB signaling pathway in inflammation by inhibiting ZMYND11 expression [PMC5021716]. In a study conducted by GenePharma in Shanghai, China, a gga-mir-19a mimic (miR-19a) and an inhibitor (miR-19a-Inh) were designed and synthesized [PMC5021716]. These results provide evidence of the role of gga-mir-19a in modulating the NF-κB signaling pathway and its potential involvement in inflammation [PMC5021716]. The study suggests that gga-mir-19a acts as a positive regulator by inhibiting ZMYND11 expression, which is known to negatively regulate NF-κB activity [PMC5021716]. The design and synthesis of gga-mir-19a mimics and inhibitors by GenePharma provide valuable tools for further investigating the role of gga-mir-19a in inflammation and its potential as a therapeutic target [PMC5021716]. These findings contribute to our understanding of the complex regulatory mechanisms involved in NF-κB signaling and highlight the importance of microRNAs, such as gga-mir-19a, in modulating inflammatory responses [PMC5021716]. Further research is needed to elucidate the precise mechanisms through which gga-mir-19a regulates NF-kB signaling and its potential therapeutic applications.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences
UGUGCAAAUCUAUGCAAAACUGA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 52 other species

  1. Alligator mississippiensis Ami-Mir-19-P1a_3p (mature (guide))
  2. Anolis carolinensis (green anole) Aca-Mir-19-P1a_3p (mature (guide))
  3. Ateles geoffroyi (black-handed spider monkey) age-miR-19a
  4. Bos taurus bta-miR-19a
  5. Callithrix jacchus cja-miR-19a
  6. Callorhinchus milii (elephant shark) Cmi-Mir-19-P1a-v1_3p (mature (guide))
  7. Canis lupus familiaris (dog) cfa-miR-19a
  8. Capra hircus (goat) chi-miR-19a
  9. Cavia porcellus cpo-miR-19a-3p
  10. Cervus elaphus cel-miR-19a
  11. Chrysemys picta bellii (western painted turtle) Cpi-Mir-19-P1a_3p (mature (guide))
  12. Columba livia (rock pigeon) cli-miR-19a-3p
  13. Cricetulus griseus cgr-miR-19a
  14. Danio rerio dre-miR-19a-3p
  15. Dasypus novemcinctus dno-miR-19a-3p
  16. Echinops telfairi Ete-Mir-19-P1a_3p (mature (guide))
  17. Equus caballus eca-miR-19a
  18. Gadus morhua gmo-miR-19a-3p
  19. Gekko japonicus Gja-Mir-19-P1a_3p (mature (guide))
  20. Gorilla gorilla gorilla ggo-miR-19a (MIR19A)
  21. Gorilla gorilla ggo-miR-19a
  22. Homo sapiens hsa-miR-19a-3p
  23. Lagothrix lagotricha lla-miR-19a
  24. Latimeria chalumnae Lch-Mir-19-P1a_3p (mature (guide))
  25. Lemur catta (Ring-tailed lemur) lca-miR-19a
  26. Macaca mulatta mml-miR-19a-3p
  27. Macaca nemestrina mne-miR-19a
  28. Microcaecilia unicolor Mun-Mir-19-P1a_3p (mature (guide))
  29. Monodelphis domestica (gray short-tailed opossum) mdo-miR-19a-3p
  30. Monopterus albus (swamp eel) Mal-Mir-19-P1a2_3p (mature (guide))
  31. Mus musculus mmu-miR-19a-3p
  32. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-19a
  33. Ophiophagus hannah oha-miR-19a-3p
  34. Ornithorhynchus anatinus oan-miR-19a-3p
  35. Oryctolagus cuniculus ocu-miR-19a-3p
  36. Ovis aries (sheep) miscellaneous RNA
  37. Pan paniscus ppa-miR-19a
  38. Pan troglodytes ptr-miR-19a
  39. Pongo pygmaeus ppy-miR-19a
  40. Python bivittatus (Burmese python) pbv-miR-19a-3p
  41. Rattus norvegicus (Norway rat) rno-miR-19a-3p
  42. Saguinus labiatus (red-chested mustached tamarin) sla-miR-19a
  43. Sarcophilus harrisii (Tasmanian devil) Sha-Mir-19-P1a_3p (mature (guide))
  44. Scyliorhinus torazame Sto-Mir-19-P1a-v1_3p (mature (guide))
  45. Sphenodon punctatus Spt-Mir-19-P1a_3p (mature (guide))
  46. Sus scrofa (pig) ssc-miR-19a
  47. Takifugu rubripes fru-miR-19a
  48. Tetraodon nigroviridis tni-miR-19a
  49. Tor tambroides (Thai mahseer) miR-19a-3p
  50. Tupaia chinensis tch-miR-19a-3p
  51. Xenopus laevis Xla-Mir-19-P1a4_3p (mature (co-guide))
  52. Xenopus tropicalis xtr-miR-19a
Publications