gga-mir-30a: The gga-mir-30a is a highly expressed miRNA that has been reported to regulate liver development and postnatal liver maturation by targeting ESRP2 [PMC5758705]. It has also been synthesized and inserted into pmirGLO vectors [PMC6406597]. Along with other miRNAs such as miR-133, miR-10b, miR-26a, and gga-miR-30e, gga-mir-30a is abundantly expressed in chicken somites [PMC4519947]. The gga-mir-30a belongs to a family of 5 members that share a seed sequence but differ at their 3' ends, allowing for an overlapping yet slightly different repertoire of targets [PMC7936154]. Studies have shown that gga-mir-30a expression is altered in the skeletal muscle during chick development and it can inhibit myoblast proliferation [PMC7936154]. Among the differentially expressed miRNAs in Gallus gallus, gga-mir-30a was found to be the highest differentially expressed one [PMC5214674].
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