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mmu-mir-30a: Mmu-mir-30a is a down-regulated miRNA after high-fat diet (HFD)-induced obesity [PMC3319598]. It has been shown to be downregulated in plasma and aorta tissue samples [PMC4346489]. Mmu-mir-30a has been found to target BDNF 3'UTR and regulate its expression [PMC9120625]. It is also involved in the regulation of SOCS3 in atherosclerotic vascular disease (ASVD) and its expression levels are significantly lower in apoE-/- aortic tissues compared to healthy controls [PMC3641397]. Mmu-mir-30a has been found to be decreased in the mPFC and hippocampus of aged rats compared to controls, and it is involved in the regulation of innate immune system-related genes [PMC6704709]. The DNA sequence of mmu-mir-30a precursor has been obtained from miRBase [PMC6764145]. Upregulation of mmu-mir-30a is associated with liver regeneration, while its downregulation is associated with abnormal morphology in podocyte models [PMC9198802] [PMC6032378]. The probes used for gene expression analysis include mmu-mir-30a [PMC7380117].
References:
[PMC3319598] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319598/
[PMC4346489] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346489/
[PMC9120625] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120625/
[PM3641397] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM3641397/
[PM6704709] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM6704709/
[PMC6764145] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764145/
[PMC9198802] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198802/
[PMC6032378] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032378/
[PMC7380117] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380117/
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