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Homo sapiens (human) Prader Willi/Angelman region RNA 6 (PWAR6) URS00004F2D30_9606

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PWAR6: PWAR6, a type of long non-coding RNA, was found to have a positive effect on the osteogenesis of human periodontal ligament stem cells (hPDLSCs) [PMC7893692]. The study suggested that the interaction between miR-106a-5p and PWAR6 played a role in the osteogenic differentiation of hPDLSCs [PMC7893692]. Additionally, Pearson analysis revealed a significant negative correlation between the expressions of PWAR6 and YAP1 [PMC8093982]. These findings indicate that PWAR6 may have a regulatory role in hPDLSC osteogenesis and that its expression may be inversely related to YAP1 expression [PMC8093982]. The study provides valuable insights into the molecular mechanisms underlying hPDLSC differentiation and highlights the potential therapeutic applications of PWAR6 in promoting bone formation [PMC7893692][PMC8093982]. Further research is needed to fully understand the functional significance of PWAR6 and its interaction with miR-106a-5p in hPDLSCs, as well as its relationship with YAP1 expression.

Targeting miRNAs 41 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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UUAUUUUUAAUAUUAUGUUGUAUUUGAUGUGCUAUCCUAUUCAUUUAGUAUAAGCACAUUUUUCUUUAUGUCUUCAGCAUAAUUAUAUGCUUUUUCAGAAUUUUAACAUCAGGACUGCUUCCAGGGUAGCUUUAUUGCCCUUUGUCUUAAGUAUGGAUUAUAGUUUUCAUUCUUUGUAUGUCAAGUAAUUUUGGAUUGUAACUUGAACUUUGAAUAUACUGUAGAAACUCUGAAUUCUAUUUUAUUCUUCUAAAACAAUAUUUCUCAGCUUCAGCACUACUGACAUUUUGAACUGGGUCAUUUUGUUUGUGUUGUUGUGUGUAUUUUGGGAGGGUACUGUUCUAUAUGCAUUGUGGGGUACUGAGUAUUAUCCUUUGUCUCCACUCACUACUUACCAGUAGCAUAACUCUCUCUCCUCCCCACAUCCCCUGCCAAAAAAUGCCUUCAGUCCUUUCUAAGCGCUCUUUUUUAUGGUGUUGGGGCCAAAAUCAUGCAUCUUUACUCACUCUUUCUCAUUGAGAGCUAUGGCUAUAAAGGGUAGUGAUACUUUUACUUAUUUAUUUUUAAGGCAAGCAGUUAACUUAGCUGGAUUCAAACUCCAGGCUGCCUCGUGUGCUGUGGGAAGCAGCCUACGCUCUAUUCAGUUCUUUUCUUUUCAUAUUGGUUGGGUUACUUUGAGUCUGGCCUACAUGAUGGGCAGUUUAGAGGUCAACCAAAGGAUUUCAGCAGAACUUAUACACAGAAUUUCAUUCAGGCUUCCCGUGUCUGAUUGGCUACAGUGUGGGAAUUUCCUCCCACUUUUCAGCCACUACUGAGGAUGCCUUUCGGCAAAAUUCCUUGAAAUUGGAAACUUACAGGGAAAUUCCUUUCCUCCAAGAGUGCGCUCUCCUCCAGUGUUGGCUUGCUUUUGGUUGUUCUCCGUGGUUUUAGAUAGCUGUCUUUAUAUUAAUUCUGGAGUUUACAGUUGAUAUCUGUUGGGGGCUUAGUUUGAUAACAUGUAUUCUUCUAUUACUAGUAGCCAGACCUGUAUGUCUUACUUGACCUGAUGGAGAAAAGUUUCAACUUAUGAGACAAUACUGUGCUAGCUAGUUUUACUGAUUUGUACUCUAAAGUACCCAAGCCUAAAAUAGUAGAGCUGUCUAUCCCACAUGAAACUUCUCUGAUUUUCACUGUUUUUUAUAAAAAGUAUACAUGUUCACAUUUCUGUAGGUUUUUUUAAGCAUCACAAUUUUUAUAAACUUUCUAUAUUUCCAAGGUCUACCUGCUUUGUAUUUUGCCUAGUGAGAGUUUUGUAUUCAUGUAGGAAUAAUCUCUUGGUGUGAGUAUCUAUUUUCCACUCAUCCAAAACAGAUAGAGCAUUGAUUUCACUAAGCGUUAUGUUCUAGUUUGCUUUGGUAUUAUUAUUAGAAAUACCUGGUGAUUAAUUUGAGCUAAGUAUUCUUCUCUACCCUCAUUCCCAGCAUUAUCACCCGCUUUUACCACUUCCAAGGGGUGGAAGCAUUCUCCACAAUGCAUUUUUUCAUGCCAGAGAAAAAUCUAGAAAAAAAUGAAUAAAACGAAGAAAUUCUUUCCCCUUGGUAUCUGUAGCUAACUUGCCUAAGUGUUCUUUCCCACAGUUUAAGUCUUCAGUCCAUAGUUCAUAAGCAAAGGGGUGUAGCGAGCUCUGAUCUUGCCAGAAGAGAGAAUAAGUGAGCUACCCCACGGUGGACAUUCUGGCCAUCUGAAAUGAGUCGAUGCAUGUGGCUUUUGUCUAAAGGCUACAAAUAAAAUGUAACCACUUUCUUCUUUGAGUAGUUGAUAUAGCAAAUAGUUGAAACAGAAGUUUUGAUUGGCAAAUCAGGAUGUGGUAGAUACUUUAACAAAGAGUAGAACUAUUACCAGUUUUAUGUGUUGCUGUUUGUAUCUCUUUCACAGUUUUGAUAAUAUCACAUCCUGGAAAGUGAAACAGAAAAUUAUUAUUCCAUUUUAAAUGACUAAAUUUGCUUUCAUGGUAUUUACAGUGAAAGAGUAAAUUAGAAAGUGAAUGGAUGACUGUUCAUGAGAAAAAGCAGGGUAAAAAGAUUUUAUUUAAUUAAUUGAAAAUAUUAGGGUCAAAACAUAGGCUUAUGUUAUGUUUUGUGAAUUGUGCUGUGUUGUAGACAUUUGAUGAGUCCUAACAUAGAAUUGAUCUAGCUCUUGAAAUACCAUUUUUGAUUGAGUAUAAAUGGGAUAUAGGCACCUUACAACUUCAGAAUUCGAGGAAGAUGAUGUGAAUCUUCCAAUUUUAUCUAUUUGAUUCAAAUGGUAUGUUUUUUCACAUUUCUCAUAAUUUCCACGUCAACUCCCAUGAUGAUCAUGCAGGAAAGCAGCAUGAUUGCACUUCUUGUAGUGCAUACCAUCACUAAAACAUAGUUACUGUCUUUCUGUGGUCUUAAGAAAAAUUCAGAAACAGCAUACCAAUGUACAUAUAAGAUAAAUAAGCUUAUGUGGUACAGUAAGUGUUCUGUUCUGAGAAAUACCUUGAUUCGUAUCCUAAUGUCUGAUGUUAUUGGUAGUUCUCAAACUUCCCCAAUUCUGCUUUCAUCUAAAUUCAUCUUAUCUAUCUAUUGUUAAAUAAUCUAUCAGUCCAUUUUUAUCUAUCAUCUAUAUAUCUGUCUUUAUCAAUCAUUCGUCUGUAAUCUAUCUGUGCCGUUUGGCAUAAGAGACAGAAGGGCAUAGCAGUGGAAACUCAAAGGAGUUACCUCCAUGUGAAUGGACAGUGGUGAUGGUGAUCUGUGAGGUGGUGAUGUAUAGAAAGAAAAACUAGAAGAGAGCAUGCCCUAACUCAGGGACCUUGUCCAGCAGGCACUCUGGCCUUGUUAUACUGUGCUUGAAUAUGAAAAAAAAAAAAAUCAAAAUAGUGCUGACAUUCUUUGUCUUCUGGGUCUGAGAAAACUUAGAGUAGAUAUGAUGACUCUGCCAUUUCAGUCUUUUGUAUUUCCACAUUUAGAGCUCAGUUUUAAUUAUGUAGAAUUAUUUCUCCAGCCUGUGUUAAACUAGACCAUGGAUUGGCAAACUUUUUUUGUAAAUUGCCAAAUACACAUUUUCAGUUCUGAAAGCCUUGUGGUCUUUGUUGCAGCUAAUCUACUCUGCUGUUGUGUUAUGAAAGCAGCCAUAGGUAAUUUAUAAUUGAAUGAGUGCGCUGUGCCUUUCUUCCAAUAAAACUUUACAAAAGCAUCCUGUGGGCUGGAGUUUACCCUUUGGGAAACCAGAGCAUUGGCUAAACUGGAACCUGAAAAAAUAAUCACAUCAACUCAGCCACAUGGUAAUAAUAUUUAGAGUAUUAUUUCAACAUUUUCAUUUUCAUAAAAAUUUUUUUAGCUCUUUUGCCAAAUUCCAUCUGUGAGUGAUACAAAUGACUACCACGUGCCAUUAACAUCACCUAAACAGUGCAAAACAAGCAUAGUAGAAGUAAUUGGAAUGAUAUAAACCCCUUGCUGUAAUAGUUAUAGUUGAUAAAUUAUGUUUCAAAAUUGAACCUAUUUCUUCCAAAUUUCAUCUAUAAAGUUCCAAGGAGUUCCAAAAUCUUGCCUGCCUUCUUUUCCCAGUUAGCAGUAUUGUCUCUGAGCAGCCAUGGUGGUAUCCAUCCUCCUUGGACAAUGAAUUUAGCCUAUUUUGACUUCAUUUGAGCAGUUGUAAUUGUUUCACCACAUCAGAGUAAGAUUACUACAUGCCAGAGCUAUUCUUUAACUCAGCUUGUAAAAACAUGAUAGCAUCAACAAUAUACAUAGCAAAUGAAUGCCAUCUUUAAUCCAAUUAAAUGGUUUUUACAAAUUUGCUCUUGUUUGUUGAUGCUAUCUGCAUUGCAGUAAUUAAAGGUGAGGUAAAAAGAAUGAAUAAACUGCCAAGUUAAAAUUAAAUUUGGGCAAUUUCUCUUUUGCAGUAAUGUAUGUAUAUUUACUCAAAACAUAUGCCAAAUUUAGUGUUGAAAGGCUCAUUCAAAUCAAUUGGGAAAGCACGUAAAUGAACAAUUCAUAAAAGAAAAGCAUUGCAAAUGGCCAAGAGCAUAGAAAAUGUGCUCAAUCUUACCAGUCAUUAUAAGGAAAUAAUGAAAUUUGUGUAUAUAUGAAAUACUUAAAAUAUAUAUAAAAUAAAACAAUUAUUUGCCUUUUUUCACCUAUCAGAUUAACAGAUUAUAUGUGUUAACAAGGUGGGGAGAAUUUACAACUCCUGAUAUGUUAAAAUCUUUCAGGAAGGUAGUAGAAAAUAUAUGUAAGAUGGAAAUUAGCACUUUUGACCAACAAUUUUAGUUUUAGAUAUUUACCUAUAAGGAUAUAAUAGGAGGUGUUCAAAGAUGCAUGUAACUCAAUGUAGUAUUAAUUAUAAUUGUAAAAUAGUAAAUAACAUUUUUGUCAAAUCAUAAUGUUAGGAAAAUUAGUGAUGGCACAUUUAACCAAUUGAAUUAUAUUCAGUUCUGAAUACCGUGAUGCAUGUUCAAAUUAAUUGAUACAAAAAUCCAACAACUUUAGCAGUUUGUUUACCAGUUAUUGAGUACCAACUGUGUUCAACAUUGUUAUUUCACUCAUAUGAAAUGAUAAAUGUAUGUGCGUGUUAUGAUACGGUCAAUAAAACCACUUUUAUAGGAAGAAUACUCACAAAA

Taxonomic tree

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