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hsa-mir-19a: Hsa-mir-19a is one of the key miRNAs identified in the study [PMC4118176]. It is a microRNA that plays a significant role in various biological processes. The study found that hsa-mir-19a, along with hsa-miR-181c and hsa-miR-19b, had higher degrees in the network diagram [PMC4118176]. The researchers performed Q-RT-PCR analysis for miR-19a and miR-19b using specific primers for hsa-mir-19a and hsa-mir-19b [PMC4139485]. This analysis allowed them to measure the expression levels of these microRNAs.
Hsa-mir-19a is a member of the miR-17~92 cluster, which is known to be involved in various biological processes, including cell proliferation, apoptosis, and development [PMC4118176]. It has been found to be dysregulated in several diseases, including cancer. In cancer research, hsa-mir-19a has been shown to act as an oncogene by promoting cell proliferation and inhibiting apoptosis [PMC4118176].
The study's findings regarding the higher degrees of hsa-miR181c, hsa-mir-19a, and hsa-miR-19b in the network diagram suggest their potential importance in cellular processes [PMC4118176]. The QRT–PCR analysis using specific primers for these microRNAs allowed for accurate measurement of their expression levels [PMC4139485].
In conclusion, hsa-mir– 19a is an important microRNA involved in various biological processes. Its dysregulation has been implicated in diseases such as cancer. The study's findings highlight its significance along with other key miRNAs identified through network analysis [PMC4118176]. The QRT–PCR analysis using specific primers for hsa-mir-19a provided valuable insights into its expression levels [PMC4139485].
mRNA interactions
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Genome locations
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