gga-mir-27b: Gga-mir-27b is a microRNA that has been found to be involved in various biological processes, including antiviral responses and fat deposition in chickens. In the context of IBDV infection, gga-mir-27b expression is increased in DF-1 cells, and it can suppress IBDV replication by upregulating the expression of IFN-β, IRF3, and NF-κB through the targeting of SOCS3 and 6 [PMC9607458]. It has been shown that gga-mir-27b is demethylated after IBDV infection, leading to increased expression of gga-miR-27b-3p [PMC7291112]. Additionally, gga-miR-27b has been found to be differentially expressed in various viral infections, including avian influenza virus infection in chicken lungs [PMC5389138]. In terms of fat deposition in chickens, gga-miR-27b is one of the miRNAs that increase significantly after sexual maturity [PMC8002044]. Furthermore, gga-mir-27b has been identified as one of the least abundant miRNAs in 8% PEG precipitated TEX [PMC7734234]. TargetScan analysis has predicted putative targets for gga-mir-27b among muscle-related miRNAs [PMC3107184]. Lastly, gga-miR-221 and gga-miR222 are among the miRNAs that are co-expressed with gga-mir-27b and can influence the function of mature DCs [PMC4735322].