ssc-mir-27b: Ssc-mir-27b is a microRNA (miRNA) that is associated with apoptosis, cell death, and cell cycle regulation [PMC3968000]. It has been found to be involved in PRRSV replication, with its impact on replication being studied using miRNA mimics and inhibitors [PMC4846818]. Ssc-mir-27b has also been identified as a disease marker in E. coli F18 infection in weaned piglets [PMC4585011]. High-throughput sequencing has shown that ssc-mir-27b is upregulated in susceptible animals and downregulated in resistant animals during E. coli F18 infection [PMC3427155]. It should be noted that ssc-mir-27b may have multiple precursor targeting regions in the genome [PMC3427155]. Additionally, ssc-mir-27b has been identified as a hub miRNA with a higher degree of connectivity [PMC6875397]. In summary, ssc-mir-27b is a microRNA associated with apoptosis, cell death, and cell cycle regulation. It plays a role in PRRSV replication and has been identified as a disease marker in E. coli F18 infection. Ssc-mir-27b may have multiple precursor targeting regions and exhibits hub-like characteristics within the miRNA network.