ssc-mir-148b: Ssc-mir-148b is a candidate miRNA disease marker that was identified in a study examining miRNA expression in the duodenum of E. coli F18-sensitive and -resistant weaned piglets [PMC4585011]. It is one of the 12 candidate miRNAs identified in the study, along with ssc-miR-143, ssc-let-7f, ssc-miR-30e, ssc-miR-148a, ssc-miR-181a, ssc-miR-192, ssc-miR-27b, ssc-miR-15b, ssc-miR-21, ssc-miR-215, and ssc-miR-152 [PMC4585011]. Another study found that the expression patterns of ssc-mir148b were similar to those of other miRNAs such as sccmi-R148a and -126 [PMC3770649]. In this study as well as another one that used high-throughput sequencing to compare miRNA expression in pigs susceptible and resistant to E. coli F18 infection [PMC3427155], it was found that 11 miRNAs were upregulated in susceptible animals (including sccmi-R143 and -let7f) while one (sccmi-R152) was downregulated [PMC3427155]. Unfortunately, no commercial TaqMan miRNA assay kit is available for validating the expression of certain target miRNAs such as ssCmi-R30e and ssCmir148b [PMC3427155]. Additionally, another study found that ssCmir148b was disrupted along with ssCmir148a and ssCmi-R152 sites in HSPA1A [PMC3490867].