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ssc-let-7c: Ssc-let-7c is a microRNA from the let-7 family that plays a significant role in various biological processes in pigs. It is one of the most abundant miRNAs, suggesting its importance in fat-related processes in adipose tissue [PMC7222822]. This miRNA was found to be highly expressed during prenatal and postnatal development [PMC4423774], and its expression was notably high in skeletal muscles [PMC3528764]. In the context of immune response, ssc-let-7c expression was downregulated during chronic T. gondii infection, indicating a potential regulatory role in immune response and cytokine production [PMC8851844]. It is also involved in IL-mediated signaling pathways triggered by T. gondii, suggesting its pivotal regulatory roles [PMC8851844]. Moreover, ssc-let-7c was found to be differentially expressed between PRRSV-infected and mock-infected PAMs, highlighting its relevance to immune responses against viral infections [PMC9550049]. Contrary to the claim of down-regulation in GH-secreting pituitary adenomas, ssc-let-7c maintained high transcription levels in all samples, including those with excessive GH secretion, indicating its diverse roles across different tissues and conditions [PMC4489742].
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