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bta-mir-33a: Bta-mir-33a is a microRNA that has been identified in various studies as having potential regulatory functions in milk fat metabolism [PMC6731312] [PMC6699390] [PMC7744623] [PMC4783934]. It has been found to negatively regulate the expression of elongation of very long chain fatty acids protein 5 (ELOVL5), elongation of very long chain fatty acids protein 6 (ELOVL6), and sterol-C4-methyl oxidase (SC4MOL) in the mammary gland with low milk fat content [PMC6699390]. Bta-mir-33a is also predicted to target genes such as ELOVL5, ELOVL6, and SC4MOL, which are up-regulated in mammary gland with low milk fat content [PMC4783934]. Furthermore, bta-mir-33a has been found to be expressed at a significantly lower level in certain mammary gland tissues [PMC4783934]. It is worth noting that the regulatory function of bta-mir-33a may vary depending on the specific tissue, organ, and physiological conditions being studied [PMC4783934]. Bta-mir-33a has also been identified as one of the differentially expressed microRNAs between preadipocytes and adipocytes, suggesting its involvement in lipid metabolism [PMC7278844]. Additionally, bta-mir-33a has been found to regulate the expression of GHRHR (ENSBTAG00000047599) through its interaction with circRNAs and miRNAs such as bta-miR-218 [PMC9821774]. Overall, bta-mir-33a appears to play an important role in milk fat metabolism and lipid metabolism pathways.
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