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rno-mir-100: Rno-mir-100 is a microRNA that has been studied in various contexts [PMC4271342]. In one study, a mutant 3'-UTR of IGF1R with a modified binding site to rno-mir-100 was created using a Site-Directed Mutagenesis Kit [PMC4271342]. Oligonucleotides of rno-mir-100 inhibitor, rno-mir-100 mimics, and non-specific control were purchased from Ribo-Bio [PMC4271342]. Comparing significantly deregulated miRNAs in different groups, it was found that rno-mir-100 showed similar expression changes in both groups at the same postoperative time point [PMC4198680]. Out of the miRNAs found to be similarly regulated, only rno-mir-100, along with rno-miR-133a, rno-miR-133b, and rno-miR-466c were consistently detected in all plasma samples [PMC4198680]. Rno-mir-100 was downregulated following certain treatments such as surgery and anesthesia [PMC4198680]. However, it was significantly upregulated following isoflurane anesthesia compared to untreated animals [PMC4198680]. TaqMan mature miR assays were used to quantify the expression levels of various miRNAs including rno-mir-100 [PMC5838212]. In another study, it was found that at 24 hours and 48 hours after treatment with certain drugs or conditions, several miRNAs including rno-mir-100 showed dysregulation [PMC5856749].
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