v24

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Ovis aries (sheep) oar-miR-181a URS00003DA300_9940

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oar-miR-181a: Oar-mir-181a is a type of microRNA that has been extensively studied in relation to sheep reproduction and immune response [PMC7992348] [PMC8300399] [PMC6339376] [PMC9679157] [PMC7070426] [PMC9222358] [PMC7142988] [PMC9464909] [PMC8532869] [PMC8902169]. It has been found to be highly expressed during the breeding season in sheep, along with Oar-miR-26a and Oar-miR-143 [PMC7992348]. Oar-mir-181a has been correlated with various target genes, including LTBP1, INSR, GREB1L, IL1RL1, SNX13, CYP11A1, COL12A1, ITGAV, and COL14A1, in relation to sheep fecundity and reproductive function [PMC8300399]. Competitive endogenous RNA network analysis has revealed target miRNA sites in circRNAs for oar-mir-181a and other miRNAs such as oar-miR-27a and oar-miR-16b, which are associated with reproductive function and immune-related genes [PMC8300399]. The expression of oar-mir-181a has been found to be both upregulated and downregulated in different experimental conditions, such as during the follicular phase compared to the luteal phase of the ovarian cycle in sheep and after immunization with B. suis strain S2 [PMC6339376] [PMC8902169]. The expression of oar-mir-181a has been validated using qPCR and RNA-seq analysis methods [PMC6339376]. Further research is needed to fully understand the functions and regulatory mechanisms of oar-mir-181a in sheep reproduction and immune response [PMC7992348] [PMC8300399] [PMC6339376] [PMC9679157] [PMC7070426] [PMC9222358] [PMC7142988] [PMC9464909] [PMC8532869] [PMC8902169].

Genome locations

Gene Ontology annotations

Sequence

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AACAUUCAACGCUGUCGGUGAGU

Taxonomic tree

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This sequence is found in 55 other species

  1. Alligator mississippiensis ami-miR-181a-5p
  2. Anolis carolinensis aca-miR-181a
  3. Bos taurus Bta-Mir-181-P1b_5p (mature (guide))
  4. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-181a
  5. Callorhinchus milii (elephant shark) Cmi-Mir-181-P1c_5p (mature (guide))
  6. Canis lupus familiaris Cfa-Mir-181-P1b_5p (mature (guide))
  7. Capra hircus miR-181a
  8. Cavia porcellus (domestic guinea pig) Cpo-Mir-181-P1b_5p (mature (guide))
  9. Cervus elaphus (red deer) cel-miR-181a
  10. Chrysemys picta bellii Cpi-Mir-181-P1b_5p (mature (guide))
  11. Chrysemys picta (Painted turtle) cpi-miR-181a-5p
  12. Columba livia Cli-Mir-181-P1b_5p (mature (guide))
  13. Cricetulus griseus (Chinese hamster) cgr-miR-181a-5p
  14. Danio rerio (zebrafish) dre-miR-181a-5p
  15. Dasypus novemcinctus Dno-Mir-181-P1b_5p (mature (guide))
  16. Daubentonia madagascariensis dma-miR-181a
  17. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-181-P1b_5p (mature (guide))
  18. Eptatretus burgeri (inshore hagfish) Ebu-Mir-181-P1f_5p (mature (guide))
  19. Equus caballus (horse) eca-miR-181a
  20. Gadus morhua (Atlantic cod) gmo-miR-181a-5p
  21. Gallus gallus gga-miR-181a-5p
  22. Gekko japonicus Gja-Mir-181-P1b_5p (mature (guide))
  23. Gorilla gorilla gorilla ggo-miR-181a-5p (MIR181A-2)
  24. Gorilla gorilla (western gorilla) ggo-miR-181a-5p
  25. Homo sapiens hsa-miR-181a-5p
  26. Lagothrix lagotricha lla-miR-181a-5p
  27. Latimeria chalumnae (coelacanth) Lch-Mir-181-P1b_5p (mature (guide))
  28. Lepisosteus oculatus Loc-Mir-181-P1b_5p (mature (guide))
  29. Macaca mulatta mml-miR-181a-5p
  30. Macaca nemestrina mne-miR-181a-5p
  31. Microcaecilia unicolor Mun-Mir-181-P1b_5p (mature (guide))
  32. Monodelphis domestica mdo-miR-181a-5p
  33. Mus musculus mmu-miR-181a-5p
  34. Nomascus leucogenys (northern white-cheeked gibbon) nle-miR-181a
  35. Ornithorhynchus anatinus oan-miR-181a-5p
  36. Oryctolagus cuniculus (rabbit) Ocu-Mir-181-P1b_5p (mature (guide))
  37. Otolemur garnettii (small-eared galago) oga-miR-181a
  38. Pan paniscus (pygmy chimpanzee) ppa-miR-181a-5p
  39. Pan troglodytes ptr-miR-181a-5p
  40. Papio hamadryas pha-miR-181a
  41. Petromyzon marinus (sea lamprey) pma-miR-181a-5p
  42. Pongo pygmaeus (Bornean orangutan) ppy-miR-181a-5p
  43. Python bivittatus Pbv-Mir-181-P1c_5p (mature (guide))
  44. Rattus norvegicus rno-miR-181a-5p
  45. Saguinus labiatus sla-miR-181a
  46. Salmo salar (Atlantic salmon) ssa-miR-181a-5p
  47. Sarcophilus harrisii Sha-Mir-181-P1b_5p (mature (guide))
  48. Scyliorhinus torazame (cloudy catshark) Sto-Mir-181-P1b_5p (mature (guide))
  49. Sphenodon punctatus Spt-Mir-181-P1b_5p (mature (guide))
  50. Taeniopygia guttata (zebra finch) tgu-miR-181a-5p
  51. Takifugu rubripes (torafugu) fru-miR-181a-5p
  52. Tetraodon nigroviridis (spotted green pufferfish) tni-miR-181a-5p
  53. Tor tambroides (Thai mahseer) miR-181a-5p
  54. Tupaia chinensis tch-miR-181a-5p
  55. Xenopus tropicalis xtr-miR-181a-5p
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