ssc-mir-133a: ssc-mir-133a is a microRNA that was found to be overexpressed in L samples in a bioinformatic screening [PMC5155628]. It was selected as a candidate for further experimental validation due to its role in reproductive-related pathways [PMC5155628]. Significant correlations were found between the expression level of ssc-mir-133a and validated differentially expressed genes related to prolificacy [PMC5155628]. ssc-mir-133a was also found to be up-regulated in the adipose tissue of Laiwu pigs and is related to adipocyte differentiation and fat metabolism [PMC9859024]. In addition, ssc-mir-133a may play a role in premolar morphogenesis, as it is differentially expressed during premolar development and may be involved in multiple pathways related to bicuspid teeth morphogenesis [PMC4696248]. It was also found to play a more important role in the early morphogenesis of premolars compared to other microRNAs [PMC4696248]. Overall, ssc-mir-133a has been implicated in reproductive-related pathways, adipocyte differentiation, fat metabolism, and premolar morphogenesis.