bta-mir-139: Bta-mir-139 is a type of mature microRNA that is assumed to share the same sequence as its human counterpart, hsa-miR-139-5p [PMC5702184]. This microRNA has been studied for its interaction with the 3′-UTR of target genes such as GHR and IGF1R, where specific binding regions have been predicted [PMC5702184]. In experimental setups, cells were co-transfected with bta-mir-139 mimic or inhibitor and a luciferase reporter construct to assess the microRNA's regulatory effects [PMC5702184]. Additionally, bta-mir-139's role in cell proliferation was investigated using MTT assays at various time points post-transfection [PMC5702184]. In the context of bovine cells, bta-mir-139 was found to be more abundant in mammary gland-derived stem cells (MDSCs) than in their progeny (MDSC-P) [PMC5415838], indicating a potential role in stem cell function or differentiation. Furthermore, bta-mir-139 has been included in networks of differentially expressed microRNAs (DEmiRNAs) and their target genes, suggesting its involvement in regulatory pathways within bovine cells [PMC6720277]. The negative regulatory relationship between bta-mir-139 and its target genes ABCC3/PDE5A was validated to understand its functional implications better [PMC6720277].