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ssc-mir-497: Ssc-mir-497 is a microRNA that was tested in a study, where qPCR amplification was performed using primers designed for the human homolog sequences, indicating 100% homology [PMC6598998]. In the study, several microRNAs were found to be up-regulated in both groups, including ssc-mir-497 [PMC6598998]. Additionally, ssc-mir-497 was found to be involved in regulating the cell cycle and Neurotrophin signaling pathway through corresponding putative target genes [PMC4934789]. Furthermore, ssc-mir-497 was highly expressed in hpiPSCs compared to mpiPSCs [PMC4934789]. The P53 signaling pathway was also regulated by ssc-mir-497 through targeting specific genes [PMC4934789]. Interestingly, ssc-mir-497 and ssc-miR-195 were highly expressed in hpiPSCs and were located in the same genome loci on chromosome 12 [PMC4934789]. Additionally, several miRNAs including ssc-miR-744 and ssc-miR-338 were reported to have important roles in myogenesis [PMC6737989], indicating their potential significance. Overall, these findings highlight the involvement of ssc-mir-497 in various cellular processes and its potential role in myogenesis.
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Gene Ontology annotations
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Sequence
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