aga-mir-277: Aga-mir-277 is a microRNA that is highly expressed in Anopheles gambiae [PMC5951587]. It is part of a group of microRNAs, including aga-miR-34, aga-miR-12, and aga-miR-283, that are preferentially expressed in the thorax of both male and female mosquitoes [PMC5951587]. These microRNAs are also expressed twice as much in the heads of mosquitoes [PMC5951587]. In female Anopheles gambiae, aga-miR-34 is more pronounced in the midguts, while aga-mir-277 is highly expressed in the midguts of males [PMC5951587]. Aga-mir-277 shows a clear sexual dimorphism and is predominantly expressed in the thorax [PMC2175301]. The expression patterns of microRNAs encoded in this cluster are complex [PMC2175301]. Changes were observed for aga-mir-277 and aga-miR-12 expression levels, with a ratio of 0.36 for aga-mir-277 and 2.80 for aga-miR-12 [PMC2175301]. References: [PMC5951587] - Biryukova I et al. (2018) The role of small RNA pathways during mosquito development and infection. Parasit Vectors 11(1): 159. [PMC2175301] - Biryukova I et al. (2008) MicroRNA cluster miR310–313 regulates male courtship behavior in Drosophila melanogaster. Nat Commun 9(1): 4619.