mmu-mir-221: Mmu-mir-221 is a microRNA that has been found to be involved in lymphoid development and is differentially expressed between distinguishable lymphocyte cell types [PMC2244641]. In a study on DIO + LFD mice, mmu-mir-221 was found to be downregulated in DIO mice [PMC4571067]. Mmu-mir-221 is an interaction partner of TOX4 and MMU-MIR-376C [PMC6391818]. In another study, the expression levels of mmu-mir-221 were assessed in relation to lung disease, but no differential expression was detected [PMC4691205]. Mmu-mir-221 was used in standard curve reactions for miRNA assays [PMC7430632]. Mmu-mir-221* has a similar expression level compared to mmu-mir-221 [PMC3421232]. Mmu-mir-221 was found to be upregulated in white adipose tissue (WAT) after high-fat diet (HFD) feeding [PMC3319598]. The upregulation of mmu-mir-221 and the downregulation of the mmu-miR-200 family were consistent with previous studies on WAT after HFD feeding [PMC3319598]. Mmu-miR-30e*, mmu-miR34c, and mmu-miR1425p were identified as differentially expressed miRNAs with high degrees of connectivity in a network analysis involving mmu-mir-221 [PMC6833270]. References: [PMC2244641]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244641/ [PMC4571067]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571067/ [PMC6391818]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391818/ [PMC4691205]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691205/ [PMC7430632]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430632/ [PMC3421232]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421232/ [PMC3319598]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319598/ [PMC6833270]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833270/